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I N Format I on Theory and the Bra In

Bok Globules in the Lmc

We report the discovery of small, isolated dust clouds in the Large Magellanic Cloud, which are excellent candidates for counterparts to the Bok globules observed in the Galaxy. We detect these small clouds silhouetted against diffuse Hα emission, based on parallel imaging with the WFPC-2 on HST. The clouds we identify as Bok globule candidates have typical sizes of approximately 1 ′′ , corresp...

BOK (Bcl2-related ovarian killer)

Alternative splicing results in expression of two mRNA variants. The full-length (Bok-L) mRNA comprises 2.6 kb with the 639 bp open reading frame. The truncated form (Bok-S) results from skipping of exon three and a deletion of 43 bp in the Bok-L coding region. It has been shown that transcription activity of the Bok gene depends on expression of p53 and can be directly regulated at the gene pr...

Star Formation in the Bok Globule Cb54

We present mid-infrared (10.4, 11.7, and 18.3 m) imaging intended to locate and characterize the suspected protostellar components within the Bok globule CB54. We detect and confirm the protostellar status for the nearinfrared source CB54YC1-II. The mid-infrared luminosity for CB54YC1-II was found to be Lmidir 8 L , and we estimate a central source mass ofM 0:8M (for a mass accretion rate of Ṁ ...

Hypoxia-inducible regulation of placental BOK expression.

BOK (BCL-2-related ovarian killer) is a member of the pro-apoptotic BCL-2 family that is highly expressed in the human placenta. BOK excess causes increased trophoblast autophagy and apoptosis in pre-eclampsia, a pathological condition of hypoxia and oxidative stress. In the present study, we identified an HRE (hypoxia-response element) at the junction of exon-1 and intron-1 (+229 to +279) in t...